- Detroit Lions: Matt Stafford, QB, Georgia
- St. Louis Rams: Jason Smith, OL, Baylor
- Kansas City Chiefs: Tyson Jackson, DE, Louisiana State
- Seattle Seahawks: Mark Sanchez, QB, Southern California
- Cleveland Browns: Aaron Curry, LB, Wake Forest
- Cinncinati Bengals: Eugene Monroe, OL, Virginia
- Oakland Raiders: Michael Crabtree, WR, Texas Tech
- Jacksonville Jaguars: Jeremy Maclin, WR, Missouri
- Green Bay Packers: Everette Brown, DE, Florida State
- San Francisco 49ers: B.J. Raji, NT, Boston College
- Buffalo Bills: Brian Orkapo, DE, Texas
- Denver Broncos: Rey Maualuga, LB, Southern California
- Washington Redskins: Michael Oher, OL, Mississippi
- New Orleans Saints: Michael Jenkins, CB, Ohio State
- Houston Texans: Vontae Davis, CB, Illinois
- San Diego Chargers: Aaron Maybin, DE, Penn State
- New York Jets: Knowshon Moreno, RB, Georgia
- Denver Broncos: Peria Jerry, DT, Mississippi
- Tampa Bay Buccaneers: Josh Freeman, QB, Kansas State
- Detroit Lions: Eben Britton, OL, Arizona
- Philadelphia Eagles: Chris "Beanie" Wells, RB, Ohio State
- Minnesota Vikings: William Beatty, OL, Connecticut
- New England Patriots: Brian Cushing, LB, Southern California
- Atlanta Falcons: James Laurinaitis, LB, Ohio State
- Miami Dolphins: Clay Matthews, LB, Southern California
- Baltimore Ravens: Darius Butler, CB, Connecticut
- Indianapolis Colts: Evander "Ziggy" Hood, DT, Missouri
- Buffalo Bills: Brandon Pettigrew, TE, Oklahoma State
- New York Giants: Percy Harvin, Florida
- Tennessee Titans: Alex Mack, OL, California
- Arizona Cardinals: Robert Ayer, DE, Tennessee
- Pittsburgh Steelers: Max Unger, OL, Oregon
